#94: Caryophyllene: Nature’s Answer to Inflammation and Pain Relief

The terpenes in cannabis play a crucial role in the plant's overall effects and aroma. They modulate the effects of cannabinoids like THC and CBD, and can contribute to a strain's unique flavour profile. One of the more prevalent terpenes found in cannabis is caryophyllene, which has become increasingly popular for its potential therapeutic effects.

Found in common foods like black pepper, cloves, and cinnamon, caryophyllene has a spicy and woody aroma that can add depth and complexity to a strain's overall scent. Picture a pungent, earthy aroma with hints of spice and you're on the right track.

 

What makes caryophyllene so special?

Plants produce terpenes as a natural defence mechanism against predators and environmental stressors. Caryophyllene, also known as beta-caryophyllene or BCP, is a sesquiterpene found in many different plant species. A sesqui-what? Simply put, sesquiterpenes are larger and more complex terpenes that have a different chemical structure than monoterpenes or diterpenes.

Common foods like black pepper, cloves, and cinnamon are all rich sources of caryophyllene. This terpene is also found in various herbs such as oregano, basil, and thyme. And of course, it can be found in our beloved cannabis.

A fascinating aspect of caryophyllene is that it's the only known terpene to interact with the body's endocannabinoid system. Yes, you read that right - this terpene can actually activate cannabinoid receptors in the body, specifically the CB2 receptor.

CB1 and CB2 receptors are found throughout the body, with CB1 primarily located in the brain and nervous system, while CB2 is more abundant in immune cells. THC, the psychoactive compound in cannabis, primarily binds to CB1 receptors, causing the euphoric and intoxicating effects associated with cannabis.

On the other hand, CBD has a higher affinity for CB2 receptors and is known for its potential anti-inflammatory and pain-relieving properties. But what about caryophyllene? Well, this terpene may also have some amazing therapeutic benefits due to its ability to interact with CB2 receptors.

 

Why caryophyllene is a game-changer

There is a substantial body of research on caryophyllene and its potential therapeutic effects. Some of the most promising include:

Anti-inflammatory properties: By activating CB2 receptors, caryophyllene may help reduce inflammation in the body. Chronic inflammation is linked to a wide range of diseases and conditions, such as arthritis, diabetes, and heart disease.

Pain relief: Along with its anti-inflammatory effects, caryophyllene may also help alleviate pain. In an animal study, researchers found that this terpene significantly reduced pain response in mice.

Neuroprotective properties: There is evidence that caryophyllene can protect brain cells from damage and potentially even promote their growth.

Antioxidant effects: Some studies have shown that this terpene has antioxidant properties, which can help protect cells from damage caused by free radicals.

Antibacterial and antifungal properties: Caryophyllene has been found to have strong antimicrobial effects against both bacteria and fungi, making it a promising natural alternative for treating infections.

Antiviral effects: Preliminary research suggests that caryophyllene may also have antiviral properties, which could make it a potential treatment for viral infections.

Addiction treatment: Animal studies have shown that caryophyllene may help reduce alcohol intake and dependence, indicating its potential as a treatment for addiction.

Anxiety and depression relief: Some evidence suggests that caryophyllene may have anxiolytic (anti-anxiety) and antidepressant effects by regulating certain neurotransmitters in the brain.

With so many potential benefits, it's no wonder that caryophyllene has caught the attention of researchers and health professionals. However, more studies are needed to fully understand its effects and potential uses in human health. But one thing is for sure, this terpene found in many plants and spices holds tremendous potential for improving our health and well-being.

 

Top picks: Strains rich in caryophyllene

At Herbal Dispatch, we stock over 300 products that contain caryophyllene, including dried flower, pre-rolls, concentrates, edibles and topicals. Here's a curated list of some of our top-selling cannabis products high in caryophyllene:

Legacy Reserve Whole Flower by J.R. Strain: The dominant terpene in this strain is caryophyllene (0.73%) and it is also high in limonene (0.59%). With a sweet, citrusy aroma and euphoric effects, this is a tasty and potent choice.

Midday Mix White Truffle by Happy Hour: It's Original Glue (aka GG4) x Peanut Butter Breath contains over 1.1% caryophyllene, along with high levels of limonene (1.03%) and humulene (0.64%) for a calming and euphoric experience.

Vice's Cake by Vertuose Culture: Straight out of Quebec, this strain Wedding Cake x Wedding Cake is high in caryophyllene (0.79%), humulene (0.39%) and limonene (0.24%) and is known for its calming and uplifting effects.

Gas Cake Pre-Rolls by Ostara: It's hard to resist this strain with its high caryophyllene content (0.9%), in addition to other terpenes like limonene (0.98%) and humulene (0.44%) that may help with stress, pain and inflammation.

Sour Animal Live Rosin by Brindle Farms: If you prefer concentrates, this live rosin contains a high amount of caryophyllene (2.54%) along with other terpenes like limonene (1.96%) and myrcene (1.45%) for a potent and flavourful experience.

GLTOZ FS Honey Oil by Retro: This one takes the cake with its caryophyllene content at a whopping 5.18%, along with farnesene (4.12%) and humulene (1.64%). It has a sweet, earthy flavour with hints of citrus and spice.

Mother of Berries FS Honey Oil Vape by Retro: Take it on the go with this vape cartridge high in caryophyllene (1.61%) and humulene (0.73%) with a sweet and fruity taste that's sure to please.

Cherry THC Indica Gummy by Emprise: Fancy a sweet treat instead? These gummies are infused with terpenes like myrcene, caryophyllene and linalool, providing a relaxing and potentially pain-relieving experience.

Sea to Sky Balm by Earthwolf farms: For topical relief for skin, joints and muscles, this balm contains caryophyllene and other terpenes like myrcene and bisabolol. Made from fresh bubble hash, shea butter, cocoa butter and candelilla wax, this balm is all-natural and soothing.

From flowers to concentrates and edibles, there are many ways to incorporate caryophyllene-rich strains and products into your wellness routine for potential pain relief and relaxation. Keep in mind that everyone's body chemistry is unique, so it may take some experimentation to find the perfect balance for you.

 

Caryophyllene: A versatile terpene for everyday wellness

As one of the most abundant terpenes in nature, caryophyllene offers a wide range of potential benefits for both physical and mental wellness. From its anti-inflammatory and pain-relieving properties to its potential for promoting relaxation and reducing anxiety, caryophyllene is a versatile compound that can be found in many cannabis products.

If you're looking to incorporate more caryophyllene into your cannabis routine, be sure to use our Terpenes Filter to easily find products high in this terpene. The journey to discovering your perfect cannabis experience is just a few clicks away. Happy exploring!

Back to all posts